論文 - 詳細
RRC ID | 29474 |
---|---|
著者 | Yamauchi N, Nakayama Y. |
タイトル | Biosynthetic mechanism for L-Gulose in main polar lipids of Thermoplasma acidophilum and possible resemblance to plant ascorbic acid biosynthesis. |
ジャーナル | Biosci Biotechnol Biochem |
Abstract |
L-Gulose is a very rare sugar, but appears as a sugar component of the main polar lipids characteristic in such a thermophilic archaeon as Thermoplasma acidophilum that lives without cell walls in a highly acidic environment. The biosynthesis of L-gulose in this thermophilic organism was investigated with deuterium-labeling experiments. L-Gulose was found to be biosynthesized from D-glucose via stepwise stereochemical inversion at C-2 and C-5. The involvement of an epimerase related to GDP-mannose 3,5-epimerase, the key enzyme of plant ascorbate biosynthesis, was also suggested in this C-5 inversion. The resemblance of L-gulose biosynthesis in archaea and plants might be suggested from these results. |
巻・号 | 77(10) |
ページ | 2087-93 |
公開日 | 2013-1-1 |
DOI | 10.1271/bbb.130442 |
PII | DN/JST.JSTAGE/bbb/130442 |
PMID | 24096672 |
MeSH | Ascorbic Acid / biosynthesis* Glucose / metabolism Hexoses / biosynthesis* Hexoses / chemistry Lipids / chemistry* Plants / metabolism* Stereoisomerism Thermoplasma |
IF | 1.516 |
引用数 | 0 |
WOS 分野 | BIOCHEMISTRY & MOLECULAR BIOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY |
リソース情報 | |
一般微生物 | JCM 9062 |