RRC ID 34391
著者 Milani C, Lugli GA, Duranti S, Turroni F, Bottacini F, Mangifesta M, Sanchez B, Viappiani A, Mancabelli L, Taminiau B, Delcenserie V, Barrangou R, Margolles A, van Sinderen D, Ventura M.
タイトル Genomic encyclopedia of type strains of the genus Bifidobacterium.
ジャーナル Appl Environ Microbiol
Abstract Bifidobacteria represent one of the dominant microbial groups that are present in the gut of various animals, being particularly prevalent during the suckling stage of life of humans and other mammals. However, the overall genome structure of this group of microorganisms remains largely unexplored. Here, we sequenced the genomes of 42 representative (sub)species across the Bifidobacterium genus and used this information to explore the overall genetic picture of this bacterial group. Furthermore, the genomic data described here were used to reconstruct the evolutionary development of the Bifidobacterium genus. This reconstruction suggests that its evolution was substantially influenced by genetic adaptations to obtain access to glycans, thereby representing a common and potent evolutionary force in shaping bifidobacterial genomes.
巻・号 80(20)
ページ 6290-302
公開日 2014-10-1
DOI 10.1128/AEM.02308-14
PII AEM.02308-14
PMID 25085493
PMC PMC4178644
MeSH Animals Bifidobacterium / genetics* Bifidobacterium / metabolism Bifidobacterium / physiology Biological Evolution* Clustered Regularly Interspaced Short Palindromic Repeats Computer Simulation Gastrointestinal Tract / microbiology Genome, Bacterial* Molecular Sequence Data Phylogeny* Sequence Analysis, DNA Species Specificity
IF 4.016
引用数 120
WOS 分野 BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY
リソース情報
一般微生物 JCM 1207 JCM 13495