RRC ID 11255
著者 Kawaoka S, Katsuma S, Meng Y, Hayashi N, Mita K, Shimada T.
タイトル Identification and characterization of globin genes from two lepidopteran insects, Bombyx mori and Samia cynthia ricini.
ジャーナル Gene
Abstract We describe the characterization of hemoglobin-like genes from two lepidopteran insects, Bombyx mori (Bmglobin) and Samia cynthia ricini (Scglobin). Bmglobin and Scglobin are predicted to be intracellular proteins and contain amino acids required for heme and oxygen binding. Expression profiles of two lepidopteran globins, especially Bmglobin, were different from that of other insect globins. Although other insect globins are mainly associated with the tracheal system, Bmglobin was expressed almost exclusively in the Malpighian tubules, and the strongest signal for Scglobin was detected in the fat body. Furthermore, biochemical fractionation analysis revealed that both Bmglobin and Scglobin were localized in the cytoplasm. These results suggest that each lepidopteran globin has a distinct role in the tissues in which it is expressed and that the functions of insect globins are more divergent than previously thought.
巻・号 431(1-2)
ページ 33-8
公開日 2009-2-15
DOI 10.1016/j.gene.2008.11.004
PII S0378-1119(08)00591-X
PMID 19059317
MeSH Amino Acid Sequence Animals Bombyx / genetics* Gene Expression Profiling Gene Expression Regulation Globins / chemistry Globins / genetics* Lepidoptera / genetics* Molecular Sequence Data Phylogeny Protein Transport Subcellular Fractions / metabolism
IF 2.984
引用数 7
WOS 分野 GENETICS & HEREDITY
リソース情報
カイコ Samia cynthia ricini p50