RRC ID 36052
著者 Kirchmaier S, Naruse K, Wittbrodt J, Loosli F.
タイトル The genomic and genetic toolbox of the teleost medaka (Oryzias latipes).
ジャーナル Genetics
Abstract The Japanese medaka, Oryzias latipes, is a vertebrate teleost model with a long history of genetic research. A number of unique features and established resources distinguish medaka from other vertebrate model systems. A large number of laboratory strains from different locations are available. Due to a high tolerance to inbreeding, many highly inbred strains have been established, thus providing a rich resource for genetic studies. Furthermore, closely related species native to different habitats in Southeast Asia permit comparative evolutionary studies. The transparency of embryos, larvae, and juveniles allows a detailed in vivo analysis of development. New tools to study diverse aspects of medaka biology are constantly being generated. Thus, medaka has become an important vertebrate model organism to study development, behavior, and physiology. In this review, we provide a comprehensive overview of established genetic and molecular-genetic tools that render medaka fish a full-fledged vertebrate system.
巻・号 199(4)
ページ 905-18
公開日 2015-4-1
DOI 10.1534/genetics.114.173849
PII 199/4/905
PMID 25855651
PMC PMC4391551
MeSH Animals Animals, Genetically Modified / genetics Genetic Engineering / methods Genome* Hybridization, Genetic* Oryzias / genetics*
IF 4.015
引用数 37
WOS 分野 GENETICS & HEREDITY
リソース情報
メダカ resource database