RRC ID 29474
著者 Yamauchi N, Nakayama Y.
タイトル Biosynthetic mechanism for L-Gulose in main polar lipids of Thermoplasma acidophilum and possible resemblance to plant ascorbic acid biosynthesis.
ジャーナル Biosci Biotechnol Biochem
Abstract L-Gulose is a very rare sugar, but appears as a sugar component of the main polar lipids characteristic in such a thermophilic archaeon as Thermoplasma acidophilum that lives without cell walls in a highly acidic environment. The biosynthesis of L-gulose in this thermophilic organism was investigated with deuterium-labeling experiments. L-Gulose was found to be biosynthesized from D-glucose via stepwise stereochemical inversion at C-2 and C-5. The involvement of an epimerase related to GDP-mannose 3,5-epimerase, the key enzyme of plant ascorbate biosynthesis, was also suggested in this C-5 inversion. The resemblance of L-gulose biosynthesis in archaea and plants might be suggested from these results.
巻・号 77(10)
ページ 2087-93
公開日 2013-1-1
DOI 10.1271/bbb.130442
PII DN/JST.JSTAGE/bbb/130442
PMID 24096672
MeSH Ascorbic Acid / biosynthesis* Glucose / metabolism Hexoses / biosynthesis* Hexoses / chemistry Lipids / chemistry* Plants / metabolism* Stereoisomerism Thermoplasma
IF 1.516
引用数 0
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY
リソース情報
一般微生物 JCM 9062