論文 - 詳細
| RRC ID | 34794 |
|---|---|
| 著者 | Dohra H, Fujishima M, Suzuki H. |
| タイトル | Analysis of amino acid and codon usage in Paramecium bursaria. |
| ジャーナル | FEBS Lett |
| Abstract |
The ciliate Paramecium bursaria harbors the green-alga Chlorella symbionts. We reassembled the P. bursaria transcriptome to minimize falsely fused transcripts, and investigated amino acid and codon usage using the transcriptome data. Surface proteins preferentially use smaller amino acid residues like cysteine. Unusual synonymous codon and amino acid usage in highly expressed genes can reflect a balance between translational selection and other factors. A correlation of gene expression level with synonymous codon or amino acid usage is emphasized in genes down-regulated in symbiont-bearing cells compared to symbiont-free cells. Our results imply that the selection is associated with P. bursaria-Chlorella symbiosis. |
| 巻・号 | 589(20 Pt B) |
| ページ | 3113-8 |
| 公開日 | 2015-9-1 |
| DOI | 10.1016/j.febslet.2015.08.033 |
| PII | S0014-5793(15)00733-4 |
| PMID | 26341535 |
| MeSH | Amino Acids / genetics* Amino Acids / metabolism Chlorella / physiology Codon / genetics* Gene Expression Profiling / methods Host-Pathogen Interactions Paramecium / genetics* Paramecium / metabolism Paramecium / microbiology Protein Biosynthesis Protozoan Proteins / genetics Protozoan Proteins / metabolism Symbiosis Transcriptome* |
| IF | 3.057 |
| 引用数 | 2 |
| WOS 分野 | BIOPHYSICS BIOCHEMISTRY & MOLECULAR BIOLOGY CELL BIOLOGY |
| リソース情報 | |
| ゾウリムシ | Yad1w (PB031012B) Yad1g1N (PB031010B) |