RRC ID |
34264
|
著者 |
Arakawa H, Takasaki M, Tajima N, Fukamachi H, Igarashi T.
|
タイトル |
Antibacterial activities of persimmon extracts relate with their hydrogen peroxide concentration.
|
ジャーナル |
Biol Pharm Bull
|
Abstract |
Persimmon, a deciduous tree of the family Ebenaceae, is found throughout East Asia and contains high levels of tannins. This class of natural compounds exhibit favorable toxicity profiles along with bactericidal activity without the emergence of resistant bacteria, suggesting potential medical applications. Consistent with these observations, persimmon leaves show antibacterial activity. However, the mechanism of persimmon antibacterial activity remains unknown. In the present work, we demonstrate that the antibacterial activity of persimmon reflects the generation of reactive oxygen from tannins. The identification and quantification of reactive oxygen generated from persimmon and the level of antibacterial activity were determined.
|
巻・号 |
37(7)
|
ページ |
1119-23
|
公開日 |
2014-1-1
|
DOI |
10.1248/bpb.b13-00952
|
PII |
DN/JST.JSTAGE/bpb/b13-00952
|
PMID |
24805207
|
MeSH |
Anti-Bacterial Agents / isolation & purification
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects
Bacteria / growth & development
Colony Count, Microbial
Diospyros / chemistry*
Hydrogen Peroxide / analysis*
Microbial Sensitivity Tests
Plant Components, Aerial / chemistry
Plant Extracts / isolation & purification
Plant Extracts / pharmacology*
|
IF |
1.863
|
引用数 |
11
|
WOS 分野
|
PHARMACOLOGY & PHARMACY
|
リソース情報 |
一般微生物 |
JCM 1134
JCM 1222
JCM 5803
JCM 20026 |