RRC ID 30180
著者 Yoshida KI, Yamaguchi M, Ikeda H, Omae K, Tsurusaki KI, Fujita Y.
タイトル The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
ジャーナル Microbiology (Reading)
Abstract The myo-inositol catabolism pathway of Bacillus subtilis has not been fully characterized but was proposed to involve step-wise multiple reactions that finally yielded acetyl-CoA and dihydroxyacetone phosphate. It is known that the iolABCDEFGHIJ operon is responsible for the catabolism of inositol. IolG catalyses the first step of myo-inositol catabolism, the dehydrogenation of myo-inositol, producing 2-keto-myo-inositol (inosose). The second step was thought to be the dehydration of inosose. Genetic and biochemical analyses of the iol genes led to the identification of iolE, encoding the enzyme for the second step of inositol catabolism, inosose dehydratase. The reaction product of inosose dehydratase was identified as D-2,3-diketo-4-deoxy-epi-inositol.
巻・号 150(Pt 3)
ページ 571-580
公開日 2004-3-1
DOI 10.1099/mic.0.26768-0
PMID 14993306
MeSH Bacillus subtilis / enzymology* Bacillus subtilis / genetics* Base Sequence DNA, Bacterial / genetics Escherichia coli / genetics Genes, Bacterial* Hydro-Lyases / genetics* Hydro-Lyases / metabolism* Inositol / analogs & derivatives* Inositol / metabolism* Operon
IF 2.138
引用数 29
WOS 分野 MICROBIOLOGY
リソース情報
原核生物(大腸菌) ME9644 ME9661 ME9662 ME9663
原核生物(枯草菌) MBS168 MBS250 MBS251 MBS252 MBS253 MBS254 MBS255 MBS256 MBS257 MBS258 MBS259