RRC ID |
30180
|
著者 |
Yoshida KI, Yamaguchi M, Ikeda H, Omae K, Tsurusaki KI, Fujita Y.
|
タイトル |
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
|
ジャーナル |
Microbiology (Reading)
|
Abstract |
The myo-inositol catabolism pathway of Bacillus subtilis has not been fully characterized but was proposed to involve step-wise multiple reactions that finally yielded acetyl-CoA and dihydroxyacetone phosphate. It is known that the iolABCDEFGHIJ operon is responsible for the catabolism of inositol. IolG catalyses the first step of myo-inositol catabolism, the dehydrogenation of myo-inositol, producing 2-keto-myo-inositol (inosose). The second step was thought to be the dehydration of inosose. Genetic and biochemical analyses of the iol genes led to the identification of iolE, encoding the enzyme for the second step of inositol catabolism, inosose dehydratase. The reaction product of inosose dehydratase was identified as D-2,3-diketo-4-deoxy-epi-inositol.
|
巻・号 |
150(Pt 3)
|
ページ |
571-580
|
公開日 |
2004-3-1
|
DOI |
10.1099/mic.0.26768-0
|
PMID |
14993306
|
MeSH |
Bacillus subtilis / enzymology*
Bacillus subtilis / genetics*
Base Sequence
DNA, Bacterial / genetics
Escherichia coli / genetics
Genes, Bacterial*
Hydro-Lyases / genetics*
Hydro-Lyases / metabolism*
Inositol / analogs & derivatives*
Inositol / metabolism*
Operon
|
IF |
2.138
|
引用数 |
29
|
WOS 分野
|
MICROBIOLOGY
|
リソース情報 |
原核生物(大腸菌) |
ME9644
ME9661
ME9662
ME9663 |
原核生物(枯草菌) |
MBS168
MBS250
MBS251
MBS252
MBS253
MBS254
MBS255
MBS256
MBS257
MBS258
MBS259 |