RRC ID 33531
著者 Kitaura T, Chikumi H, Murota H, Fujiwara H, Touge H, Okada K, Nakamoto M, Igishi T, Burioka N, Yaguchi T, Shimizu E.
タイトル [A case of lung abscess due to Aspergillus viridinutans in a patient with aplastic anemia].
ジャーナル Kansenshogaku Zasshi
Abstract A 75-year-old woman with aplastic anemia was admitted to our university hospital because of a dry cough that had persisted for a month. Chest computed tomography showed a mass shadow with a central low attenuation area in the lower lobe of the left lung. Filamentous fungus resembling Aspergillus fumigatus was cultured from the specimens obtained by transthoracic needle aspiration biopsy and bronchoalveolar lavage. The initial diagnosis was a lung abscess due to A. fumigatus, although the patient did not respond well to antifungal agents. Subsequently, the filamentous fungus was identified as Aspergillus viridinutans by sequence analysis of the β-tubulin gene, and the patient was successfully treated with combination therapy along with granulocyte colony-stimulating factor. The incidence of A. viridinutans infection is very rare. A. viridinutans is morphologically similar to A. fumigatus; however, the response to antifungal agents is generally worse than that observed in A. fumigatus infections. Therefore, the selection of agents and supplemental therapy is of vital importance in cases of A. viridinutans infection.
巻・号 88(6)
ページ 855-60
公開日 2014-11-1
DOI 10.11150/kansenshogakuzasshi.88.855
PMID 25764808
MeSH Aged Anemia, Aplastic / complications* Aspergillus / isolation & purification* Female Humans Lung Abscess / microbiology*
リソース情報
病原微生物 IFM 5058 IFM 41090 IFM 42277 IFM 47064 IFM 47457 IFM 53867 IFM 54302 IFM 54303 IFM 54304 IFM 61579