RRC ID |
42261
|
著者 |
Yamada M, Matsuura N, Suzuki H, Kurosaka C, Hasegawa N, Ubukata M, Tanaka T, Iinuma M.
|
タイトル |
Germacranolides from Calea urticifolia.
|
ジャーナル |
Phytochemistry
|
Abstract |
Four germacranolides, named calealactones A-C and calealactone B [corrected] were isolated from the leaves of Calea urticifolia (Compositae) in addition to three known germacranolides. Their structures were established on the basis of spectroscopic analysis including by 2D NMR spectroscopy. Calealactone C and 2,3-epoxyjuanisulamin displayed potent toxicity to U937 cells.
|
巻・号 |
65(23)
|
ページ |
3107-11
|
公開日 |
2004-12-1
|
DOI |
10.1016/j.phytochem.2004.08.040
|
PII |
S0031-9422(04)00424-8
|
PMID |
15541738
|
MeSH |
Antineoplastic Agents, Phytogenic / isolation & purification
Antineoplastic Agents, Phytogenic / pharmacology
Asteraceae / chemistry*
Humans
Leukemia
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Leaves / chemistry
Sesquiterpenes, Germacrane / chemistry*
Sesquiterpenes, Germacrane / isolation & purification
Sesquiterpenes, Germacrane / pharmacology
U937 Cells
|
IF |
3.044
|
引用数 |
25
|
WOS 分野
|
PLANT SCIENCES
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
リソース情報 |
ヒト・動物細胞 |
U-937 DE-4(RCB0435) |