| RRC ID |
3512
|
| 著者 |
Hashimoto K, Mega K, Matsumoto Y, Bao Y, Yamano Y, Morishima I.
|
| タイトル |
Three peptidoglycan recognition protein (PGRP) genes encoding potential amidase from eri-silkworm, Samia cynthia ricini.
|
| ジャーナル |
Comp Biochem Physiol B Biochem Mol Biol
|
| Abstract |
Three cDNA clones encoding peptidoglycan recognition proteins (PGRP-B, -C and -D) were isolated from larval fat body of immunized Samia cynthia ricini. The deduced amino acid sequences show high homology to each other and also to Drosophila PGRP-LB, but rather lower homology to all of the known lepidopteran PGRPs including Samia PGRP-A, a receptor-type PGRP. The three PGRPs conserve the five amino acid residues which form the catalytic site of N-acetylmuramoyl L-alanine amidase as in Drosophila LB. The PGRP-C and -D genes were silent in naive larvae, but strongly induced in fat body by an injection of peptidoglycan. PGRP-B gene, in contrast, constitutively expressed at high levels in naive midgut, and the gene was weakly induced in fat body after injection of peptidoglycan.
|
| 巻・号 |
148(3)
|
| ページ |
322-8
|
| 公開日 |
2007-11-1
|
| DOI |
10.1016/j.cbpb.2007.06.011
|
| PII |
S1096-4959(07)00226-6
|
| PMID |
17689997
|
| MeSH |
Amidohydrolases / chemistry
Amidohydrolases / genetics*
Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
Bombyx / enzymology*
Carrier Proteins / chemistry
Carrier Proteins / genetics*
Cloning, Molecular
DNA, Complementary
Isoenzymes / chemistry
Isoenzymes / genetics*
Molecular Sequence Data
Sequence Homology, Amino Acid
|
| IF |
2.219
|
| 引用数 |
15
|
|
WOS 分野
|
ZOOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| リソース情報 |
| カイコ |
Samia cynthia ricini |
