論文 - 詳細
| RRC ID | 28158 |
|---|---|
| 著者 | Xu L, Law SR, Murcha MW, Whelan J, Carrie C. |
| タイトル | The dual targeting ability of type II NAD(P)H dehydrogenases arose early in land plant evolution. |
| ジャーナル | BMC Plant Biol |
| Abstract |
BACKGROUND:Type II NAD(PH) dehydrogenases are located on the inner mitochondrial membrane of plants, fungi, protists and some primitive animals. However, recent observations have been made which identify several Arabidopsis type II dehydrogenases as dual targeted proteins. Targeting either mitochondria and peroxisomes or mitochondria and chloroplasts. RESULTS:Members of the ND protein family were identified in various plant species. Phylogenetic analyses and subcellular targeting predictions were carried out for all proteins. All ND proteins from three model plant species Arabidopsis, rice and Physcomitrella were cloned as N- and C-terminal GFP fusions and subcellular localisations were determined. Dual targeting of plant type II dehydrogenases was observed to have evolved early in plant evolution and to be widespread throughout different plant species. In all three species tested dual targeting to both mitochondria and peroxisomes was found for at least one NDA and NDB type protein. In addition two NDB type proteins from Physcomitrella were also found to target chloroplasts. The dual targeting of NDC type proteins was found to have evolved later in plant evolution. CONCLUSIONS:The functions of type II dehydrogenases within plant cells will have to be re-evaluated in light of this newly identified subcellular targeting information. |
| 巻・号 | 13 |
| ページ | 100 |
| 公開日 | 2013-7-10 |
| DOI | 10.1186/1471-2229-13-100 |
| PII | 1471-2229-13-100 |
| PMID | 23841539 |
| PMC | PMC3716789 |
| MeSH | Amino Acid Sequence Embryophyta / classification Embryophyta / enzymology* Embryophyta / genetics Evolution, Molecular* Molecular Sequence Data NAD / metabolism NADP / metabolism Oxidoreductases / genetics* Oxidoreductases / metabolism Phylogeny Plant Proteins / genetics* Plant Proteins / metabolism Protein Transport |
| IF | 3.497 |
| 引用数 | 19 |
| WOS 分野 | PLANT SCIENCES |
| リソース情報 | |
| シロイヌナズナ / 植物培養細胞・遺伝子 | pdr14501 pdr30168 pdp06608 |