RRC ID 45288
著者 Suzuki-Nakagawa C, Nishimura M, Noda M, Iwata H, Hattori M, Ebihara A, Suzuki F, Nakagawa T.
タイトル Intracellular retention of the extracellular domain of the (pro)renin receptor in mammalian cells.
ジャーナル Biosci Biotechnol Biochem
Abstract As a component of the renin-angiotensin system, the (pro)renin receptor [(P)RR] activates prorenin along with intracellular signaling pathways. In this study, the glutathione S-transferase-fused extracellular domain of (P)RR expressed in mammalian cells was recovered in the detergent phase in detergent-based two-phase separation experiments, and intracellular localization was observed by immunocytochemistry, suggesting retention inside the cell through stable membrane association.
巻・号 78(7)
ページ 1187-90
公開日 2014-1-1
DOI 10.1080/09168451.2014.915732
PMID 25229855
MeSH Animals COS Cells Chlorocebus aethiops Extracellular Space / metabolism* Hep G2 Cells Humans Intracellular Space / metabolism* Prorenin Receptor Protein Structure, Tertiary Protein Transport Receptors, Cell Surface / chemistry* Receptors, Cell Surface / metabolism* Renin-Angiotensin System
IF 1.516
引用数 5
WOS 分野 FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
ヒト・動物細胞 COS-7(RCB0539)