RRC ID 45278
著者 Nishikawa H, Noshita T, Tai A, Ouchi H, Okamoto T, Saito A, Yamada T, Iomori A, Ishimata N.
タイトル Syntheses and biological activities of the proposed structure of apteniol A and its derivatives.
ジャーナル Biosci Biotechnol Biochem
Abstract We describe the syntheses of the proposed structure of diphenyl ether oxyneolignan, apteniol A and its derivatives. The diphenyl ether moiety of proposed apteniol A was formed via Ullmann ether synthesis, but the spectral data of the synthesized apteniol A did not agree with that in previous studies. The dimethyl ester derivative of the proposed apteniol A was found to enhance neurite outgrowth in PC12 cells and inhibit antigen-induced degranulation in RBL-2H3 cells.
巻・号 78(9)
ページ 1485-9
公開日 2014-1-1
DOI 10.1080/09168451.2014.930322
PMID 25209495
MeSH Animals Cell Degranulation / drug effects Cell Degranulation / immunology Ether / chemical synthesis Ether / chemistry* Ether / pharmacology Lignans / chemical synthesis Lignans / chemistry* Lignans / pharmacology Mast Cells / drug effects Neurites / drug effects* Neurogenesis / drug effects PC12 Cells Rats
IF 1.516
引用数 3
WOS 分野 FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
ヒト・動物細胞 PC-12(RCB0009)