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Reference detail
Reference Info.
Pubmed ID 21911492  
RRC ID 12705 
Author Kumadaki S, Karasawa T, Matsuzaka T, Ema M, Nakagawa Y, Nakakuki M, Saito R, Yahagi N, Iwasaki H, Sone H, Takekoshi K, Yatoh S, Kobayashi K, Takahashi A, Suzuki H, Takahashi S, Yamada N, Shimano H. 
Title Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice. 
Journal J Biol Chem. 
Published 2011-11-25 
Volume 286(47) 
Pages 40835-46 
DOI 10.1074/jbc.M111.235283   
PII M111.235283 
Cell Cycle / drug effects
Cell Cycle / genetics
Cell Proliferation / drug effects
F-Box Proteins / genetics
F-Box Proteins / metabolism*
Fatty Liver / genetics
Fatty Liver / metabolism*
Fatty Liver / pathology
Fenofibrate / pharmacology
Gene Knockdown Techniques
Kruppel-Like Transcription Factors / metabolism*
Lipid Metabolism / drug effects
Lipid Metabolism / genetics
Liver / drug effects
Liver / metabolism
Liver / pathology
Mice, Inbred C57BL
PPAR gamma / deficiency
PPAR gamma / genetics
PPAR gamma / metabolism*
Sterol Regulatory Element Binding Protein 1 / metabolism*
Ubiquitin-Protein Ligases / deficiency
Ubiquitin-Protein Ligases / genetics
Ubiquitin-Protein Ligases / metabolism*
Resource Info.
Species DNA material 
Resource name
AxCANCre (RDB01748

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