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Reference Info.
Pubmed ID 20460758  
RRC ID 18924 
Author Matsuda T, Kondo A, Tsunashima Y, Togari A. 
Title Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts. 
Journal Biol. Pharm. Bull. 
Published 2010-5-13 
Volume 33(5) 
Pages 804-8 
PII JST.JSTAGE/bpb/33.804 
Bone Neoplasms / drug therapy
Bone Neoplasms / metabolism
Cell Line
Cell Proliferation* / drug effects
Cyclooxygenase 2 / metabolism
Cyclooxygenase Inhibitors
Dinoprostone / biosynthesis
Enzyme Inhibitors
Flavonoids / pharmacology
Glutamic Acid / biosynthesis
Imidazoles / pharmacology
Interleukin-1 / metabolism
Interleukin-1beta / genetics
Interleukin-1beta / metabolism*
Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors
Mitogen-Activated Protein Kinase Kinases / metabolism*
Nitrobenzenes / pharmacology
Osteoblasts / cytology
Osteoblasts / drug effects
Osteoblasts / metabolism*
Osteocalcin / metabolism*
Osteosarcoma / drug therapy
Osteosarcoma / metabolism
Protein Kinase Inhibitors / metabolism
Pyridines / pharmacology
RNA, Messenger / metabolism
Receptors, Steroid / metabolism
Reverse Transcriptase Polymerase Chain Reaction
Rifampin / pharmacology
Sulfonamides / pharmacology
Vitamin K / pharmacology*
Vitamins / pharmacology*
Warfarin / pharmacology
Young Adult
p38 Mitogen-Activated Protein Kinases / antagonists & inhibitors
Resource Info.
Species Human and Animal Cells 
Resource name
HOS (RCB0992) Saos-2 (RCB0428

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