RRC ID 29195
著者 Nishizawa M, Kataoka K, Goto N, Fujiwara KT, Kawai S.
タイトル v-maf, a viral oncogene that encodes a "leucine zipper" motif.
ジャーナル Proc Natl Acad Sci U S A
Abstract We have molecularly cloned the provirus of the avian musculoaponeurotic fibrosarcoma virus AS42. Nucleotide sequence analysis of a biologically active clone of AS42 showed that this virus encodes a viral oncogene, maf. The deduced amino acid sequence of the v-maf gene product contains a "leucine zipper" motif similar to that found in a number of DNA binding proteins, including the gene products of the fos, jun, and myc oncogenes. However, unlike these oncogenes, the cellular maf gene was not transcriptionally activated by growth stimulation of cultured cells.
巻・号 86(20)
ページ 7711-5
公開日 1989-10-1
DOI 10.1073/pnas.86.20.7711
PMID 2554284
PMC PMC298140
MeSH Amino Acid Sequence Animals Avian Sarcoma Viruses / genetics* Base Sequence Cells, Cultured Chickens Cloning, Molecular Genes, Viral* Molecular Sequence Data Oncogene Proteins, Viral / genetics Oncogenes* Restriction Mapping Sequence Homology, Nucleic Acid Transfection
IF 9.412
引用数 225
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
遺伝子材料 pSae-2 (RDB01395)