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Reference detail
Reference Info.
Pubmed ID 25744456  
RRC ID 36758 
Author Okina Y, Takeuchi F, Yokomichi T, Takada Y, Kataoka T. 
Title Cardenolide aglycones inhibit tumor necrosis factor α-induced expression of intercellular adhesion molecule-1 at the translation step by blocking Na⁺/K⁺-ATPase. 
Journal Biol. Pharm. Bull. 
Published 2015-3-7 
Volume 38(1) 
Pages 39-47 
DOI 10.1248/bpb.b14-00532   
Cell Line
Cell Line, Tumor
Cell Survival / drug effects
Digitoxigenin / pharmacology*
Digoxigenin / pharmacology*
Intercellular Adhesion Molecule-1 / genetics
Intercellular Adhesion Molecule-1 / metabolism*
Ouabain / analogs & derivatives*
Ouabain / pharmacology
Protein Biosynthesis / drug effects
RNA, Messenger / metabolism
RNA, Small Interfering / genetics
Sodium-Potassium-Exchanging ATPase / antagonists & inhibitors*
Sodium-Potassium-Exchanging ATPase / genetics
Sodium-Potassium-Exchanging ATPase / metabolism
Tumor Necrosis Factor-alpha / metabolism*
Resource Info.
Species Human and Animal Cells 
Resource name
Hep G2 cells (RCB1648), rat fibroblast 3Y1-B clone 1–6(RCB0488) cells29 

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