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Reference Info.
Pubmed ID 25670854  
RRC ID 36791 
Author Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M. 
Title Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2. 
Journal J. Biol. Chem. 
Published 2015-2-12 
Volume 290(16) 
Pages 10368-81 
DOI 10.1074/jbc.M114.613018   
PII M114.613018 
Amino Acid Motifs
Cell Cycle Proteins / antagonists & inhibitors
Cell Cycle Proteins / genetics*
Cell Cycle Proteins / metabolism
Cell Differentiation
Cyclin B / genetics*
Cyclin B / metabolism
Cyclin-Dependent Kinases / genetics*
Cyclin-Dependent Kinases / metabolism
F-Box Proteins / antagonists & inhibitors
F-Box Proteins / genetics*
F-Box Proteins / metabolism
GATA2 Transcription Factor / antagonists & inhibitors
GATA2 Transcription Factor / genetics*
GATA2 Transcription Factor / metabolism
Gene Expression Regulation
Glycogen Synthase Kinase 3 / genetics
Glycogen Synthase Kinase 3 / metabolism
HEK293 Cells
HeLa Cells
K562 Cells
Mice, Knockout
Molecular Sequence Data
Proteasome Endopeptidase Complex / metabolism
Protein Binding
RNA, Small Interfering / genetics
RNA, Small Interfering / metabolism
Signal Transduction
Ubiquitin / genetics
Ubiquitin / metabolism
Ubiquitin-Protein Ligases / antagonists & inhibitors
Ubiquitin-Protein Ligases / genetics*
Ubiquitin-Protein Ligases / metabolism
Resource Info.
Species Human and Animal Cells 
Resource name

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