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Reference detail
Reference Info.
Pubmed ID 24389478  
RRC ID 44837 
Author Takeuchi M, Niimi T, Masumoto M, Orita M, Yokota H, Yamamoto T. 
Title Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening. 
Journal Biol. Pharm. Bull. 
Published 2014-1-7 
Volume 37(1) 
Pages 31-6 
PII DN/JST.JSTAGE/bpb/b13-00495 
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology*
Antineoplastic Agents / therapeutic use
Computer Simulation*
Drug Discovery / methods*
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology*
Enzyme Inhibitors / therapeutic use
Inhibitory Concentration 50
K562 Cells
Leukemia / drug therapy
Leukemia / enzymology*
NAD / biosynthesis*
Niacinamide / metabolism
Nicotinamide Mononucleotide / biosynthesis
Nicotinamide Phosphoribosyltransferase / antagonists & inhibitors*
Resource Info.
Species Human and Animal Cells 
Resource name

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