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Reference Info.
Pubmed ID 25446083  
RRC ID 45382 
Author Watanuki Z, Kosai H, Osanai N, Ogama N, Mochizuki M, Tamai K, Yamaguchi K, Satoh K, Fukuhara T, Maemondo M, Ichinose M, Nukiwa T, Tanaka N. 
Title Synergistic cytotoxicity of afatinib and cetuximab against EGFR T790M involves Rab11-dependent EGFR recycling. 
Journal Biochem. Biophys. Res. Commun. 
Published 2014-12-3 
Volume 455(3-4) 
Pages 269-76 
DOI 10.1016/j.bbrc.2014.11.003   
PII S0006-291X(14)01996-2 
MeSH
Animals
Antibodies, Monoclonal / chemistry
Antibodies, Monoclonal, Humanized / pharmacology*
Antineoplastic Agents / pharmacology*
Apoptosis
Apoptosis Regulatory Proteins / metabolism
Bcl-2-Like Protein 11
COS Cells
Cell Membrane / metabolism
Cercopithecus aethiops
Cetuximab
Dose-Response Relationship, Drug
Drug Resistance, Neoplasm
HeLa Cells
Humans
K562 Cells
Membrane Proteins / metabolism
Microscopy, Confocal
Microscopy, Fluorescence
Mutation
Proto-Oncogene Proteins / metabolism
Quinazolines / pharmacology*
Receptor, Epidermal Growth Factor / genetics
Receptor, Epidermal Growth Factor / metabolism*
rab GTP-Binding Proteins / metabolism*
Resource Info.
Species Human and Animal Cells 
Resource name
 

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