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Reference detail
Reference Info.
Pubmed ID 25545059  
RRC ID 45424 
Author Takasugi N, Sasaki T, Shinohara M, Iwatsubo T, Tomita T. 
Title Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity. 
Journal Biochem. Biophys. Res. Commun. 
Published 2014-12-30 
Volume 457(2) 
Pages 194-9 
DOI 10.1016/j.bbrc.2014.12.087   
PII S0006-291X(14)02276-1 
Amyloid Precursor Protein Secretases / metabolism*
Amyloid beta-Peptides / biosynthesis*
Apoptosis / drug effects
Benzyl Alcohols / chemistry
Benzyl Alcohols / pharmacology*
CHO Cells
Ceramides / chemistry*
HEK293 Cells
Morpholines / chemistry*
Morpholines / pharmacology
Mutation / genetics
Peptide Fragments / biosynthesis*
Up-Regulation / drug effects
Resource Info.
Species Human and Animal Cells 
Resource name

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