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Reference Info.
Pubmed ID 28209720  
RRC ID 47689 
Author Nakata Y, Ueda T, Nagamachi A, Yamasaki N, Ikeda KI, Sera Y, Takubo K, Kanai A, Oda H, Sanada M, Ogawa S, Tsuji K, Ebihara Y, Wolff L, Honda ZI, Suda T, Inaba T, Honda H. 
Title Acquired expression of Cbl(Q367P) in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia. 
Journal Blood 
Published 2017-2-18 
Volume 129(15) 
Pages 2148-2160 
DOI 10.1182/blood-2016-06-724658   
PII blood-2016-06-724658 
Amino Acid Substitution
Cell Cycle*
Gene Expression Regulation, Enzymologic
Hematopoietic Stem Cells* / metabolism
Hematopoietic Stem Cells* / pathology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / metabolism
Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / pathology
Leukemia, Myeloid, Acute / genetics
Leukemia, Myeloid, Acute / metabolism
Leukemia, Myeloid, Acute / pathology
Mice, Transgenic
Monocytes / metabolism
Monocytes / pathology
Monomeric GTP-Binding Proteins / biosynthesis
Monomeric GTP-Binding Proteins / genetics
Mutation, Missense*
Phosphatidylinositol 3-Kinases / genetics
Phosphatidylinositol 3-Kinases / metabolism
Proto-Oncogene Proteins c-akt / genetics
Proto-Oncogene Proteins c-akt / metabolism
Proto-Oncogene Proteins c-cbl* / biosynthesis
Proto-Oncogene Proteins c-cbl* / genetics
Signal Transduction
Resource Info.
Species Mice 
Resource name

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