論文 - 詳細
RRC ID | 67077 |
---|---|
著者 | Inaba H, Yamamoto T, Iwasaki T, Kabir AMR, Kakugo A, Sada K, Matsuura K. |
タイトル | Stabilization of microtubules by encapsulation of the GFP using a Tau-derived peptide. |
ジャーナル | Chem Commun (Camb) |
Abstract |
We constructed GFP-encapsulated microtubules (MTs) using a Tau-derived peptide which binds to their interior. The encapsulation of the GFP dramatically increased the rigidity of MTs, resulting in their enhanced velocity on a kinesin-coated substrate. Moreover, the GFP-encapsulated MTs were significantly more stable than normal MTs. |
巻・号 | 55(62) |
ページ | 9072-9075 |
公開日 | 2019-8-11 |
DOI | 10.1039/c9cc04345d |
PMID | 31268098 |
MeSH | Green Fluorescent Proteins / chemistry* Microtubules / chemistry* Models, Molecular Particle Size Peptides / chemistry* Surface Properties tau Proteins / chemistry* |
IF | 5.996 |
リソース情報 | |
遺伝子材料 | pMal-c2X MBP-GFP1-10 (RDB17883) |