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Reference Info.
Pubmed ID 14730359  
RRC ID 2391 
Author Tanaka M, Machida Y, Niu S, Ikeda T, Jana NR, Doi H, Kurosawa M, Nekooki M, Nukina N. 
Title Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease. 
Journal Nat. Med. 
Published 2004-1-20 
Volume 10(2) 
Pages 148-54 
DOI 10.1038/nm985   
PII nm985 
Brain / cytology
Brain / metabolism
Brain / pathology
Cell Death / physiology
Cell Line
Disease Models, Animal
Glucose / administration & dosage
Glucose / metabolism
Huntingtin Protein
Huntington Disease / drug therapy*
Huntington Disease / metabolism
Huntington Disease / pathology*
Liver / cytology
Liver / metabolism
Liver / pathology
Mice, Transgenic
Motor Activity / physiology
Myoglobin / genetics
Myoglobin / metabolism
Nerve Tissue Proteins / genetics
Nerve Tissue Proteins / metabolism
Neurons / metabolism
Nuclear Proteins / genetics
Nuclear Proteins / metabolism
Peptides / metabolism*
Trehalose / therapeutic use*
Resource Info.
Species Mice 
Resource name

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