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Reference Info.
Pubmed ID 20603890  
RRC ID 6862 
Author Maldonado AR, Klanke C, Jegga AG, Aronow BJ, Mahller YY, Cripe TP, Crombleholme TM. 
Title Molecular engineering and validation of an oncolytic herpes simplex virus type 1 transcriptionally targeted to midkine-positive tumors. 
Journal J Gene Med 
Published 2010-7-7 
Volume 12(7) 
Pages 613-23 
DOI 10.1002/jgm.1479   
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic / pathology
Cytotoxicity, Immunologic
Gene Knockdown Techniques
Genetic Engineering / methods*
Herpesvirus 1, Human / genetics*
Herpesvirus 1, Human / physiology
Luciferases / genetics
Mice, Nude
Nerve Growth Factors / metabolism*
Nerve Sheath Neoplasms / genetics
Nerve Sheath Neoplasms / therapy*
Oncolytic Virotherapy / methods*
Oncolytic Viruses / genetics*
Oncolytic Viruses / physiology
RNA, Small Interfering / metabolism
Survival Analysis
Transcription, Genetic*
Transgenes / genetics
Virus Replication / physiology
Xenograft Model Antitumor Assays
Resource Info.
Species DNA material 
Resource name
pKM2L-phMK (RDB05514

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