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Reference Info.
Pubmed ID 20624856  
RRC ID 28601 
Author Kanao T, Venderova K, Park DS, Unterman T, Lu B, Imai Y. 
Title Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila. 
Journal Hum. Mol. Genet. 
Published 2010-7-14 
Volume 19(19) 
Pages 3747-58 
DOI 10.1093/hmg/ddq289   
PII ddq289 
Amino Acid Sequence
Apoptosis Regulatory Proteins / metabolism
Bcl-2-Like Protein 11
Cell Line
Cell Survival
Dopamine / metabolism
Drosophila Proteins / chemistry
Drosophila Proteins / genetics
Drosophila Proteins / metabolism*
Drosophila melanogaster / cytology
Drosophila melanogaster / enzymology*
Drosophila melanogaster / growth & development
Drosophila melanogaster / ultrastructure
Eye / enzymology
Eye / growth & development
Eye / pathology
Eye / ultrastructure
Forkhead Transcription Factors / chemistry
Forkhead Transcription Factors / genetics
Forkhead Transcription Factors / metabolism*
Membrane Proteins / metabolism
Molecular Sequence Data
Nerve Degeneration / metabolism
Nerve Degeneration / pathology
Neurons / metabolism
Neurons / pathology*
Neurons / ultrastructure
Neuropeptides / metabolism
Protein-Serine-Threonine Kinases / metabolism*
Proto-Oncogene Proteins / metabolism
Transcription, Genetic
Resource Info.
Species DNA material, Drosophila 
Resource name
pUAST-dFoxO (RDB07961); pBluescriptSKII(+)-dFoxO (RDB07960

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