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Reference Info.
Pubmed ID 21979051  
RRC ID 12545 
Author McDermott-Roe C, Ye J, Ahmed R, Sun XM, Serafín A, Ware J, Bottolo L, Muckett P, Cañas X, Zhang J, Rowe GC, Buchan R, Lu H, Braithwaite A, Mancini M, Hauton D, Martí R, García-Arumí E, Hubner N, Jacob H, Serikawa T, Zidek V, Papousek F, Kolar F, Cardona M, Ruiz-Meana M, García-Dorado D, Comella JX, Felkin LE, Barton PJ, Arany Z, Pravenec M, Petretto E, Sanchis D, Cook SA. 
Title Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function. 
Journal Nature 
Published 2011-10-8 
Volume 478(7367) 
Pages 114-8 
DOI 10.1038/nature10490   
PII nature10490 
Body Weight / genetics
Cardiomegaly / enzymology*
Cardiomegaly / genetics
Cardiomegaly / pathology*
Cardiomegaly / physiopathology
Cell Respiration
Chromosomes, Mammalian / genetics
Crosses, Genetic
Endodeoxyribonucleases / deficiency
Endodeoxyribonucleases / genetics
Endodeoxyribonucleases / metabolism*
Gene Expression Regulation
Genes, Mitochondrial / genetics
Hypertrophy, Left Ventricular / enzymology
Hypertrophy, Left Ventricular / genetics
Hypertrophy, Left Ventricular / pathology
Hypertrophy, Left Ventricular / physiopathology
Lipid Metabolism
Mitochondria / genetics
Mitochondria / metabolism*
Mitochondria / pathology
Organ Size / genetics
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Quantitative Trait Loci / genetics
RNA-Binding Proteins / metabolism
Rats, Inbred Strains
Reactive Oxygen Species / metabolism
Receptors, Estrogen / metabolism
Transcription Factors / metabolism
Resource Info.
Species Rats 
Resource name

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