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Reference Info.
Pubmed ID 23986448  
RRC ID 29436 
Author Ishizaki Y, Hayashi C, Inoue K, Igarashi M, Takahashi Y, Pujari V, Crick DC, Brennan PJ, Nomoto A. 
Title Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45. 
Journal J Biol Chem. 
Published 2013-10-18 
Volume 288(42) 
Pages 30309-19 
DOI 10.1074/jbc.M113.492173   
PII M113.492173 
Antitubercular Agents / pharmacology*
Azepines / pharmacokinetics*
Bacillus subtilis / enzymology
Bacillus subtilis / genetics
Bacterial Proteins / antagonists & inhibitors
Bacterial Proteins / genetics
Bacterial Proteins / metabolism
Cell Wall / enzymology*
Cell Wall / genetics
Galactans / biosynthesis
Galactans / genetics
Mycobacterium tuberculosis / enzymology*
Mycobacterium tuberculosis / genetics
Transferases / antagonists & inhibitors
Transferases / genetics
Transferases / metabolism
Transferases (Other Substituted Phosphate Groups) / antagonists & inhibitors*
Transferases (Other Substituted Phosphate Groups) / genetics
Transferases (Other Substituted Phosphate Groups) / metabolism
Tuberculosis, Multidrug-Resistant / drug therapy
Tuberculosis, Multidrug-Resistant / enzymology
Tuberculosis, Multidrug-Resistant / genetics
Resource Info.
Species General Microbes 
Resource name

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