RRC ID 11107
Author White-Cooper H.
Title Studying how flies make sperm--investigating gene function in Drosophila testes.
Journal Mol Cell Endocrinol
Abstract The majority of the audience at the European Testis Workshop were actively researching mammalian spermatogenesis or sperm function. In this paper therefore I follow the brief I had for my contribution to the meeting in the session "non-mammalian models of spermatogenesis", which was to explain practical approaches to research in Drosophila spermatogenesis, illuminating how what we learn in model organisms can be relevant to male fertility research in mammals. I discuss techniques and resources available to fly spermatogenesis researchers, and indicate how I have applied them in my lab to understand regulation of gene expression in spermatogenesis.
Volume 306(1-2)
Pages 66-74
Published 2009-7-10
DOI 10.1016/j.mce.2008.11.026
PII S0303-7207(08)00557-1
PMID 19101606
MeSH Animals Drosophila / cytology Drosophila / genetics* Male Meiosis Spermatogenesis / genetics Spermatozoa / cytology Spermatozoa / metabolism* Testis / cytology Testis / metabolism* Transcription, Genetic
IF 3.871
Times Cited 21