RRC ID |
17584
|
著者 |
Sugimoto N, Iwaki T, Chardwiriyapreecha S, Shimazu M, Kawano M, Sekito T, Takegawa K, Kakinuma Y.
|
タイトル |
Atg22p, a vacuolar membrane protein involved in the amino acid compartmentalization of Schizosaccharomyces pombe.
|
ジャーナル |
Biosci Biotechnol Biochem
|
Abstract |
The fission yeast Schizosaccharomyces pombe has a homolog of the budding yeast Atg22p, which is involved in spore formation (Mukaiyama H. et al., Microbiology, 155, 3816-3826 (2009)). GFP-tagged Atg22p in the fission yeast was localized to the vacuolar membrane. Upon disruption of atg22, the amino acid levels of the cellular fraction as well as the vacuolar fraction decreased. The uptake of several amino acids, such as lysine, histidine, and arginine, was impaired in atg22Δ cells. S. pombe Atg22p plays an important role in the compartmentalization of amino acids.
|
巻・号 |
75(2)
|
ページ |
385-7
|
公開日 |
2011-1-1
|
DOI |
10.1271/bbb.100747
|
PII |
JST.JSTAGE/bbb/100747
|
PMID |
21307582
|
MeSH |
Amino Acids / metabolism*
Autophagy-Related Proteins
Biological Transport
Membrane Proteins / metabolism*
Schizosaccharomyces / cytology*
Schizosaccharomyces / metabolism*
Schizosaccharomyces pombe Proteins / metabolism*
Vacuoles / metabolism*
|
IF |
1.516
|
引用数 |
4
|
WOS 分野
|
FOOD SCIENCE & TECHNOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
CHEMISTRY, APPLIED
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
リソース情報 |
酵母 |
S. Pombe Plasmid |