RRC ID 17584
著者 Sugimoto N, Iwaki T, Chardwiriyapreecha S, Shimazu M, Kawano M, Sekito T, Takegawa K, Kakinuma Y.
タイトル Atg22p, a vacuolar membrane protein involved in the amino acid compartmentalization of Schizosaccharomyces pombe.
ジャーナル Biosci Biotechnol Biochem
Abstract The fission yeast Schizosaccharomyces pombe has a homolog of the budding yeast Atg22p, which is involved in spore formation (Mukaiyama H. et al., Microbiology, 155, 3816-3826 (2009)). GFP-tagged Atg22p in the fission yeast was localized to the vacuolar membrane. Upon disruption of atg22, the amino acid levels of the cellular fraction as well as the vacuolar fraction decreased. The uptake of several amino acids, such as lysine, histidine, and arginine, was impaired in atg22Δ cells. S. pombe Atg22p plays an important role in the compartmentalization of amino acids.
巻・号 75(2)
ページ 385-7
公開日 2011-1-1
DOI 10.1271/bbb.100747
PII JST.JSTAGE/bbb/100747
PMID 21307582
MeSH Amino Acids / metabolism* Autophagy-Related Proteins Biological Transport Membrane Proteins / metabolism* Schizosaccharomyces / cytology* Schizosaccharomyces / metabolism* Schizosaccharomyces pombe Proteins / metabolism* Vacuoles / metabolism*
IF 1.516
引用数 4
WOS 分野 FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
酵母 S. Pombe Plasmid