| RRC ID |
249
|
| 著者 |
Naruse K, Hori H, Shimizu N, Kohara Y, Takeda H.
|
| タイトル |
Medaka genomics: a bridge between mutant phenotype and gene function.
|
| ジャーナル |
Mech Dev
|
| Abstract |
Recent advances in medaka genetics have proven that the medakafish is an excellent model system for developmental and evolutionary biology studies and that it can complement similar studies in zebrafish. Large-scale mutagenesis projects are now being conducted by several groups in Japan and are delivering a vastly expanded pool of medaka mutant stocks. This growing availability of genomic resources will greatly accelerate progress in moving from mutant phenotypes to the elucidation of gene function. This phenotype-driven approach can be expected to lead to the identification and characterization of novel genes and pathways in vertebrate genomes. This review discusses the current state of medaka genomic resources, the state of medaka gene mapping and medaka genome sequencing projects.
|
| 巻・号 |
121(7-8)
|
| ページ |
619-28
|
| 公開日 |
2004-7-1
|
| DOI |
10.1016/j.mod.2004.04.014
|
| PII |
S0925477304000954
|
| PMID |
15210171
|
| MeSH |
Animals
Biological Evolution
Chromosome Mapping
Expressed Sequence Tags
Genomics*
Mutation
Oryzias / embryology
Oryzias / genetics*
Phenotype
Sequence Analysis, DNA
|
| IF |
2.126
|
| 引用数 |
62
|
|
WOS 分野
|
DEVELOPMENTAL BIOLOGY
|
| リソース情報 |
| メダカ |
Review |
