論文 - 詳細
RRC ID | 30073 |
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著者 | Demple B, Halbrook J, Linn S. |
タイトル | Escherichia coli xth mutants are hypersensitive to hydrogen peroxide. |
ジャーナル | J Bacteriol |
Abstract |
Escherichia coli mutants lacking exonuclease III (xthA) are exceptionally sensitive to hydrogen peroxide. They are killed by H2O2 at 20 times the rate of wild-type bacteria and at 3 to 4 times the rate of recA cells. This is the first clear phenotypic sensitivity reported for xth- E. coli and should aid in clarifying peroxide-induced lethality and the in vivo role of exonuclease III. |
巻・号 | 153(2) |
ページ | 1079-82 |
公開日 | 1983-2-1 |
DOI | 10.1128/jb.153.2.1079-1082.1983 |
PMID | 6337115 |
PMC | PMC221738 |
MeSH | Catalase / metabolism Escherichia coli / drug effects* Escherichia coli / enzymology Escherichia coli / genetics Exodeoxyribonucleases / physiology* Hydrogen Peroxide / pharmacology* Mutation Phenotype |
IF | 3.006 |
引用数 | 191 |
WOS 分野 | MICROBIOLOGY |
リソース情報 | |
原核生物(大腸菌) | ME7765 |