RRC ID 30073
著者 Demple B, Halbrook J, Linn S.
タイトル Escherichia coli xth mutants are hypersensitive to hydrogen peroxide.
ジャーナル J Bacteriol
Abstract Escherichia coli mutants lacking exonuclease III (xthA) are exceptionally sensitive to hydrogen peroxide. They are killed by H2O2 at 20 times the rate of wild-type bacteria and at 3 to 4 times the rate of recA cells. This is the first clear phenotypic sensitivity reported for xth- E. coli and should aid in clarifying peroxide-induced lethality and the in vivo role of exonuclease III.
巻・号 153(2)
ページ 1079-82
公開日 1983-2-1
DOI 10.1128/jb.153.2.1079-1082.1983
PMID 6337115
PMC PMC221738
MeSH Catalase / metabolism Escherichia coli / drug effects* Escherichia coli / enzymology Escherichia coli / genetics Exodeoxyribonucleases / physiology* Hydrogen Peroxide / pharmacology* Mutation Phenotype
IF 3.006
引用数 191
WOS 分野 MICROBIOLOGY
リソース情報
原核生物(大腸菌) ME7765