Reference - Detail
| RRC ID | 55807 |
|---|---|
| Author | Bernhardsgrütter I, Vögeli B, Wagner T, Peter DM, Cortina NS, Kahnt J, Bange G, Engilberge S, Girard E, Riobé F, Maury O, Shima S, Zarzycki J, Erb TJ. |
| Title | The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite. |
| Journal | Nat. Chem. Biol. |
| Abstract |
. As one of the smallest multireaction chambers described in biology, PCS may inspire the engineering of a new class of dynamically regulated nanoreactors. |
| Volume | 14(12) |
| Pages | 1127-1132 |
| Published | 2018-12 |
| DOI | 10.1038/s41589-018-0153-x |
| PII | 10.1038/s41589-018-0153-x |
| PMID | 30374166 |
| PMC | PMC6499725 |
| MeSH | Acyl Coenzyme A / metabolism* Catalysis Coenzyme A Ligases / chemistry* Coenzyme A Ligases / genetics Coenzyme A Ligases / metabolism* Crystallography, X-Ray Kinetics Protein Domains Recombinant Fusion Proteins / chemistry Recombinant Fusion Proteins / genetics Recombinant Fusion Proteins / metabolism Scattering, Small Angle Sphingomonadaceae / enzymology Sphingomonadaceae / genetics X-Ray Diffraction |
| IF | 13.843 |
| Resource | |
| Prokaryotes E. coli | DH5α, BL21(DE3) |