RRC ID 55807
Author Bernhardsgrütter I, Vögeli B, Wagner T, Peter DM, Cortina NS, Kahnt J, Bange G, Engilberge S, Girard E, Riobé F, Maury O, Shima S, Zarzycki J, Erb TJ.
Title The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite.
Journal Nat. Chem. Biol.
Abstract . As one of the smallest multireaction chambers described in biology, PCS may inspire the engineering of a new class of dynamically regulated nanoreactors.
Volume 14(12)
Pages 1127-1132
Published 2018-12
DOI 10.1038/s41589-018-0153-x
PII 10.1038/s41589-018-0153-x
PMID 30374166
PMC PMC6499725
MeSH Acyl Coenzyme A / metabolism* Catalysis Coenzyme A Ligases / chemistry* Coenzyme A Ligases / genetics Coenzyme A Ligases / metabolism* Crystallography, X-Ray Kinetics Protein Domains Recombinant Fusion Proteins / chemistry Recombinant Fusion Proteins / genetics Recombinant Fusion Proteins / metabolism Scattering, Small Angle Sphingomonadaceae / enzymology Sphingomonadaceae / genetics X-Ray Diffraction
IF 13.843
Resource
Prokaryotes E. coli DH5α, BL21(DE3)