| RRC ID |
59826
|
| 著者 |
Nakai S, Uchitomi R, Matsuda R, Onishi T, Hatazawa Y, Kamei Y.
|
| タイトル |
Screening dataset of food components that enhance transcriptional activity of PGC1-beta.
|
| ジャーナル |
Data Brief
|
| Abstract |
PGC-1β is a transcriptional co-activator of nuclear receptors, which acts to increase energy expenditure. PGC-1β fused to GAL4 DNA-binding domain transfected in HEK293T cells showed a reporter luciferase activity. We screened food-derived and natural compounds using a reporter assay system to measure the transcriptional activity of PGC-1β. We found that soy-derived isoflavones, genistein and daidzein, and several resveratrols activated PGC-1β, see "Genistein, daidzein, and resveratrols stimulate PGC-1β-mediated gene expression" [1]. The list of 166 compounds and their reporter activity is shown here.
|
| 巻・号 |
23
|
| ページ |
103814
|
| 公開日 |
2019-4-1
|
| DOI |
10.1016/j.dib.2019.103814
|
| PII |
S2352-3409(19)30165-9
|
| PMID |
31372459
|
| PMC |
PMC6660609
|
| 引用数 |
0
|
| リソース情報 |
| ヒト・動物細胞 |
293(RCB1637) |
