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  • Search Condition : Filter (MeSH = Adaptor Proteins, Signal Transducing / metabolism*)
Species Resource
C.elegans tm544 , tm659 , tm3515 ATX-3, CDC-48 and UBXN-5: a new trimolecular complex in Caenorhabditis elegans.
C.elegans tm1031 The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.
C.elegans tm1137 The ALP-Enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase.
C.elegans tm1060 AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling.
Drosophila GS strains BTB protein, dKLHL18/CG3571, serves as an adaptor subunit for a dCul3 ubiquitin ligase complex.
Medaka HdrR-II1 (IB178) Ol4E-T, a eukaryotic translation initiation factor 4E-binding protein of medaka fish (Oryzias latipes), can interact with nanos3 and vasa in vitro.
Mice GFP-LC3#53 (RBRC00806) Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation.
Mice Nrf2 knockout mouse/C57BL6J(RBRC01390) Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage.
DNA material pRx nZ ires Neo (RDB01699). Proliferation and survival signaling from both Jak2-V617F and Lyn involving GSK3 and mTOR/p70S6K/4EBP1 in PVTL-1 cell line newly established from acute myeloid leukemia transformed from polycythemia vera.
Arabidopsis / Cultured plant cells, genes pda08829 The Arabidopsis adaptor protein AP-3μ interacts with the G-protein β subunit AGB1 and is involved in abscisic acid regulation of germination and post-germination development.
Drosophila 11107R-2 The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses.
Mice VinexinKO/C57B6(RBRC01732) Vinexin-β deficiency protects against cerebral ischaemia/reperfusion injury by inhibiting neuronal apoptosis.
Mice C57BL/6・129 SH2-B -/-(RBRC00994) SH2B1 is critical for the regulation of cardiac remodelling in response to pressure overload.
Arabidopsis / Cultured plant cells, genes pda01483 A Gatekeeper Residue of ClpS1 from Arabidopsis thaliana Chloroplasts Determines its Affinity Towards Substrates of the Bacterial N-End Rule.
Drosophila The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.
DNA material pco12 EGFR (RDB01276) , CSII-EF-MCS (RDB04378). ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
Mice Emx1-Cre KI Δneo(RBRC01345) JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.
DNA material , Xenopus tropicalis RDB6727 X. laevis whole embryo(stage 10.5) EST clones (XL151H21) The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin.
DNA material pGL4.12-mouse IFN-g promoter(600bp) (RDB16732) , pcDNA3-FLAG-mouse IkappaB-zeta(L) (RDB16730) , pcDNA3-FLAG-mouse IkappaB-zeta(S) (RDB16731) , pMY-FLAG-mouse IkB-zeta(L)-IRES-GFP (RDB16733) , pMY-FLAG-mouse IkB-zeta(S)-IRES-GFP (RDB16734) Control of IFN-γ production and regulatory function by the inducible nuclear protein IκB-ζ in T cells.