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論文 - 一覧

  • 17 Hits
  • 検索条件 : 絞込み (MeSH = Amyloid beta-Protein Precursor / metabolism*)
生物種 リソース名 タイトル
ヒト・動物細胞 LoVo(RCB1639) Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors.
遺伝子材料 Alcadein a-FLAG /pcDNA3.1(+) (RDB19587) , Alcadein b-FLAG /pcDNA3.1(+) (RDB19588) , Alcadein g-FLAG /pcDNA3.1(+) (RDB19589) Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.
ヒト・動物細胞 PC-12(RCB0009) Cucurbitacin B induces neurogenesis in PC12 cells and protects memory in APP/PS1 mice.
ヒト・動物細胞 MG6(RCB2403) An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
ヒト・動物細胞 COS-7(RCB0539) TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes.
ショウジョウバエ 1973R-3 Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model.
遺伝子材料 pTU1-PalphaAPP (RDB08714) O-Mannosylation is required for the solubilization of heterologously expressed human beta-amyloid precursor protein in Saccharomyces cerevisiae.
ショウジョウバエ FoxO mediates APP-induced AICD-dependent cell death.
ゼブラフィッシュ Tg(isl1:GFP)/rw0 β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CSII-CMV-MCS (RDB04377). FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis.
遺伝子材料 Human ILEI / pcDNA6 (RDB13040) , Human ILEI-siRNA / pSUP (RDB13041). The FAM3 superfamily member ILEI ameliorates Alzheimer's disease-like pathology by destabilizing the penultimate amyloid-β precursor.
ショウジョウバエ NP6590 (DGRC#105275) Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
ヒト・動物細胞 B16 melanoma(RCB1283) , GM95(RCB1026) Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.
線虫 Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors.
遺伝子材料 pco12 EGFR (RDB01276) Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimer's V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner.