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  • Search Condition : Filter (MeSH = Antineoplastic Agents, Alkylating / pharmacology*)
Species Resource Title
Human and Animal Cells ME-180(RCB2160) , Ca Ski(RCB1947) Targeting the mutant PIK3CA gene by DNA-alkylating pyrrole-imidazole polyamide in cervical cancer.
Human and Animal Cells U251(RCB0468) , T98G(RCB1954) The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling.
Human and Animal Cells T98G(RCB1954) , A172(RCB2530) The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status.
Human and Animal Cells U-87 MG(RCB0419) , U251(RCB0461) Downregulation of TRAP1 sensitizes glioblastoma cells to temozolomide chemotherapy through regulating metabolic reprogramming.
Human and Animal Cells NB69(RCB0480) Direct Targeting of MYCN Gene Amplification by Site-Specific DNA Alkylation in Neuroblastoma.
DNA material CS-RfA-ETV (RDB08020) , CS-RfA-ETR (RDB08362) , CSII-EF-MCS-IRES2-hKO1 (RDB07915) , CSII-EF-MCS-IRES2-Venus (RDB04384) , CS-RfA-ETBsd (RDB07917) , pENTR4-H1tetOx1 (RDB07916). Genetic regulation of the RUNX transcription factor family has antitumor effects.
Human and Animal Cells TGBC1TKB(RCB1129) Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models.
Human and Animal Cells TGBC2TKB(RCB1130) The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
Human and Animal Cells TGBC2TKB(RCB1130) Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest.
Mice RBRC00904 Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype.