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  • Search Condition : Filter (MeSH = Basic Helix-Loop-Helix Transcription Factors / metabolism*)
Species Resource Title
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) BHLHE41/DEC2 Expression Induces Autophagic Cell Death in Lung Cancer Cells and Is Associated with Favorable Prognosis for Patients with Lung Adenocarcinoma.
C.elegans tm1446 , tm295 Piecemeal regulation of convergent neuronal lineages by bHLH transcription factors in Caenorhabditis elegans.
Arabidopsis / Cultured plant cells, genes pst16228 Leucoanthocyanidin Dioxygenase in Arabidopsis thaliana: characterization of mutant alleles and regulation by MYB-BHLH-TTG1 transcription factor complexes.
Zebrafish RIKEN WT Retinoic acid controls proper head-to-trunk linkage in zebrafish by regulating an anteroposterior somitogenetic rate difference.
C.elegans tm1978 Host-commensal interaction promotes health and lifespan in Caenorhabditis elegans through the activation of HLH-30/TFEB-mediated autophagy.
C.elegans A conserved cysteine-based redox mechanism sustains TFEB/HLH-30 activity under persistent stress.
C.elegans tm1108 , tm1133 , tm1107 Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30.
C.elegans tm1978 C9orf72/ALFA-1 controls TFEB/HLH-30-dependent metabolism through dynamic regulation of Rag GTPases.
Human and Animal Cells ATDC5(RCB0565) HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development.
Human and Animal Cells TE-10(RCB2099) , TE-11(RCB2100) , TE-5(RCB1949) Podoplanin-mediated TGF-β-induced epithelial-mesenchymal transition and its correlation with bHLH transcription factor DEC in TE-11 cells.
Human and Animal Cells 201B7(HPS0063) Neuronal differentiation of human iPS cells induced by baicalin via regulation of bHLH gene expression.
Human and Animal Cells DU145(RCB2143) , PC-3(RCB2145) Basic helix-loop-helix transcription factor DEC2 functions as an anti-apoptotic factor during paclitaxel-induced apoptosis in human prostate cancer cells.
Human and Animal Cells ATDC5(RCB0565) C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
Human and Animal Cells HuH-7 TCF12 promotes the tumorigenesis and metastasis of hepatocellular carcinoma via upregulation of CXCR4 expression.
Human and Animal Cells RCC10RGB(RCB1151) A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
C.elegans tm1978 , tm4063 Insulin-like peptides and the mTOR-TFEB pathway protect Caenorhabditis elegans hermaphrodites from mating-induced death.
C.elegans tm1978 , tm4324 , tm1974 , tm1954 , tm4498 , tm4417 Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.
C.elegans tm985 , tm1978 , tm4450 Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
C.elegans HLH-2/E2A Expression Links Stochastic and Deterministic Elements of a Cell Fate Decision during C. elegans Gonadogenesis.
C.elegans tm1978 DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity.