生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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KP4(RCB1005)
|
56687
|
Population Pharmacokinetics of Liposomal Irinotecan in Patients With Cancer.
|
Clin Pharmacol Ther |
2017-12-1 |
Pubmed
Full text
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ヒト・動物細胞
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HSC-2(RCB1945)
,
HSC-3(RCB1975)
,
SAS(RCB1974)
,
Ca9-22(RCB1976)
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56017
|
Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.
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Oncol Rep |
2018-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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RAW 264(RCB0535)
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52559
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CPT-11-Induced Delayed Diarrhea Develops via Reduced Aquaporin-3 Expression in the Colon.
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Int J Mol Sci |
2018-1-6 |
Pubmed
Full text
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ヒト・動物細胞
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PC-3(RCB2145)
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52375
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Solubility-Improved 10-O-Substituted SN-38 Derivatives with Antitumor Activity.
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ChemMedChem |
2017-10-20 |
Pubmed
Full text
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ヒト・動物細胞
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NIH:OVCAR-3(RCB2135)
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51906
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Investigation of Bioequivalence Between Brand-name and Generic Irinotecan Products.
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Anticancer Res |
2016-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
|
51594
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Phosphorylated retinoblastoma protein is a potential predictive marker of irinotecan efficacy for colorectal cancer.
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Int J Oncol |
2016-3-1 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
,
A549(RCB0098)
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45369
|
An on-chip small intestine-liver model for pharmacokinetic studies.
|
J Lab Autom |
2015-6-1 |
Pubmed
Full text
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ヒト・動物細胞
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U251(RCB0461)
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44259
|
Combination therapy of cilengitide with belotecan against experimental glioblastoma.
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Int J Cancer |
2013-8-1 |
Pubmed
Full text
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ヒト・動物細胞
|
GSS(RCB2277)
,
HGC-27(RCB0500)
,
CW-2(RCB0778)
,
CACO-2(RCB0988)
|
43577
|
Identification of a potent epigenetic biomarker for resistance to camptothecin and poor outcome to irinotecan-based chemotherapy in colon cancer.
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Int J Oncol |
2012-1-1 |
Pubmed
Full text
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ヒト・動物細胞
|
|
43066
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Irinotecan-induced apoptosis is inhibited by increased P-glycoprotein expression and decreased p53 in human hepatocellular carcinoma cells.
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Biol Pharm Bull |
2007-8-1 |
Pubmed
Full text
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ヒト・動物細胞
|
|
43029
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Irinotecan activates p53 with its active metabolite, resulting in human hepatocellular carcinoma apoptosis.
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J Pharmacol Sci |
2007-7-1 |
Pubmed
Full text
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ヒト・動物細胞
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EC-GI-10(RCB0774)
|
42158
|
The expressions of p21 and pRB may be good indicators for the sensitivity of esophageal squamous cell cancers to CPT-11: Cell proliferation activity correlates with the effect of CPT-11.
|
Cancer Sci |
2004-5-1 |
Pubmed
Full text
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ヒト・動物細胞
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PC-12(RCB0009)
|
39863
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Inductions of fibroblast-like morphology and high growth activity by low-dose CPT-11 in PC12 cells: role of tenascin.
|
Toxicol In Vitro |
2000-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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U-87 MG(RCB0419)
|
39000
|
Induction of apoptosis in multi-drug resistant (MDR) human glioblastoma cells by SN-38, a metabolite of the camptothecin derivative CPT-11.
|
Cancer Chemother Pharmacol |
1997-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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K562(RCB0027)
|
38946
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Stimulation of interleukin-1beta-converting enzyme activity during growth inhibition by CPT-11 in the human myeloid leukemia cell line K562.
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Biochem Mol Med |
1996-2-1 |
Pubmed
Full text
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ヒト・動物細胞
|
|
38448
|
Hepatocyte growth factor suppresses the anticancer effect of irinotecan by decreasing the level of active metabolite in HepG2 cells.
|
Biochem Pharmacol |
2011-12-1 |
Pubmed
Full text
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ヒト・動物細胞
|
CACO-2(RCB0988)
,
CW-2(RCB0778)
|
36959
|
Irinotecan induces cell cycle arrest, but not apoptosis or necrosis, in Caco-2 and CW2 colorectal cancer cell lines.
|
Pharmacology |
2015-1-1 |
Pubmed
Full text
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原核生物(大腸菌)
|
|
3248
|
MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (beta-D-glucuronate).
|
Biochem Pharmacol |
2005-10-1 |
Pubmed
Full text
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ヒト・動物細胞
|
GCIY(RCB0555)
,
GT3TKB(RCB0885)
,
HGC-27(RCB0500)
,
HuH-6(RCB1367)
,
RBE(RCB1292)
,
SSP-25(RCB1293)
,
HuL-1
|
1470
|
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
|
Mol Cancer Ther |
2005-3-1 |
Pubmed
Full text
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