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  • Search Condition : Filter (MeSH = Cell Transformation, Neoplastic / genetics*)
Species Resource Title
Human and Animal Cells 32D(RCB1145) In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , CS-RfA-EVBsd (RDB06090) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target.
Human and Animal Cells Ba/F3(RCB0805) Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.
Human and Animal Cells LLC(RCB0558) , B16 melanoma(RCB1283) Suppressed rate of carcinogenesis and decreases in tumour volume and lung metastasis in CXCL14/BRAK transgenic mice.
Human and Animal Cells 293T(RCB2202) , Jurkat Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome.
Human and Animal Cells MC3T3-G2/PA6(RCB1127) Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.
Human and Animal Cells HuH-7 Loss of FBP1 facilitates aggressive features of hepatocellular carcinoma cells through the Warburg effect.
Human and Animal Cells Huh-7 MicroRNA-1291 targets the FOXA2-AGR2 pathway to suppress pancreatic cancer cell proliferation and tumorigenesis.
Human and Animal Cells LC-2/ad(RCB0440) , Lu-134-A(RCB0466) , Lu-140(RCB0470) Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis.
Drosophila 4005R-2 The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis.
DNA material pFLAG-CMV-5a-RPL5 (RDB17329) , pFLAG-CMV-5a-RPL11 (RDB17330) GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.
Human and Animal Cells KGN(RCB1154) The four and a half LIM domains 2 (FHL2) regulates ovarian granulosa cell tumor progression via controlling AKT1 transcription.
DNA material pKM2L-phIL1B (RDB05526) TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.
DNA material pCALNL5 (RDB01862). Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice.
Human and Animal Cells Hepa 1-6(RCB1638) The DNA methylation profile of liver tumors in C3H mice and identification of differentially methylated regions involved in the regulation of tumorigenic genes.
Human and Animal Cells MKN1(RCB1003) Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2/TIS21 via downregulating cytoplasmic nucleolin expression.
Human and Animal Cells 293T(RCB2202) EPSIN 3, A Novel p53 Target, Regulates the Apoptotic Pathway and Gastric Carcinogenesis.
DNA material , Human and Animal Cells AxCANCre (RDB01748). , T3M-12(RCB2281) , Lu-134-A(RCB0466) , Lu-138(RCB1785) , Lu-139(RCB0469) , Lu-140(RCB0470) , Lu-141(RCB1772) , Lu-143(RCB1773) , Lu-165(RCB1184) , 87-5(RCB2092) , ... PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Human and Animal Cells TE-15(RCB1951) Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis.