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  • Search Condition : Filter (MeSH = Cilia / metabolism*)
Species Resource Title
DNA material pMRX-bsr-EGFP-P2A-Rab34  (RDB18392) , pEF-FLAG-Rab34-S1A  (RDB18393) , pEF-FLAG-Rab34-deltaN (RDB18394) , pEGFP-C1-Rab34-T66N  (RDB18395) A comprehensive analysis of Rab GTPases reveals a role for Rab34 in serum starvation-induced primary ciliogenesis.
Human and Animal Cells P19.CL6 RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis.
Zebrafish off-limit rw689 Microtubules are required for the maintenance of planar cell polarity in monociliated floorplate cells.
Human and Animal Cells 201B7(HPS0063) Transplantation of multiciliated airway cells derived from human iPS cells using an artificial tracheal patch into rat trachea.
C.elegans tm4200 , tm2355 , tm2393 , tm3310 A CCRK and a MAK Kinase Modulate Cilia Branching and Length via Regulation of Axonemal Microtubule Dynamics in Caenorhabditis elegans.
C.elegans tm6235 EFHC1, implicated in juvenile myoclonic epilepsy, functions at the cilium and synapse to modulate dopamine signaling.
Zebrafish Tg(sox17:EGFP) EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.
DNA material pCDNA5-Frt-CAG-Arl13bCerulean-Fucci2a (RDB16057) , pRosa26-CAG-floxNeo-Arl13bCerulean-Fucci2a (RDB16058) , pCAG-Arl13bCerulean-Fucci2a (RDB16059) , pCAG-Fucci2a (RDB13080) , pROSA-floxNeo-Fucci2a (RDB13081) A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice.
DNA material Genome Network Project Human cDNA Clone IRAL028A16 (HGY091216) Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking.
DNA material Genome Network Project Human cDNA Clone , IRAL016M21 (HGY086709) , IRAL028A16 (HGY091216) , IRAL034P23 (HGY093983) Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking.
C.elegans tm6493 A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis.
C.elegans tm925 , tm2705 , tm3100 , tm2452 A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4.
C.elegans tm3067 , tm2705 , tm2547 , tm3100 The hydrolethalus syndrome protein HYLS-1 regulates formation of the ciliary gate.
Human and Animal Cells DT40(RCB1464) Regulation of axon arborization pattern in the developing chick ciliary ganglion: Possible involvement of caspase 3.
C.elegans tm4182 CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.
C.elegans tm324 , tm3310 , tm3360 , tm3389 , tm3871 , tm3889 , tm4059 Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia.
Medaka Hatching enzyme , d-rR/TOKYO (MT837) Loss of zinc finger MYND-type containing 10 (zmynd10) affects cilia integrity and axonemal localization of dynein arms, resulting in ciliary dysmotility, polycystic kidney and scoliosis in medaka (Oryzias latipes).
DNA material CSII-EF-MCS (RDB04378). EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.
DNA material Genome Network Project Human cDNA Clone IRAL009C12 (HGY083660) , IRAK069L05 (HGX027869) , IRAK069G14 (HGX027758) , pCAG2-EGFP-C1-IFT122 (RDB15190) , pCAG2-mCherry-C1-IFT122 (RDB15191) , pCAG2-EGFP-C1-IFT140 (RDB15192) , pCAG2-mCherry-C1-IFT140 (RDB15193) , pEGFP-C1-TULP3 (RDB15194) , pmCherry-C1-TULP3 (RDB15195). Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.
DNA material Genome Network Project human cDNA clone IRAK140P09 (HGX056369) , pCAG-EGFP-C-KIF17 (RDB15196) , pCAG-mCherry-C-KIF17 (RDB15197). Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.