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  • Search Condition : Filter (MeSH = Cytidine Deaminase / metabolism*)
Species Resource
Mice A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.
DNA material pCMV5a-AID-c-Myc-His (RDB08057) Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.
DNA material pmAID-ER-FBG (RDB07086) De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination.
Human and Animal Cells DT40(RCB1464) , 293T(RCB2202) SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.
DNA material pAID-GTOP (RDB03000) , pmAID BSSK (RDB02864). Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme.
Human and Animal Cells MKN45 (RCB1001) Modulation of activation-induced cytidine deaminase by curcumin in Helicobacter pylori-infected gastric epithelial cells.
Mice B6.Cg-Tg(CAG-cre)CZ-MO2Osb Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation.
Human and Animal Cells DT40 Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). Role of activation-induced cytidine deaminase in the progression of follicular lymphoma.
Human and Animal Cells Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.