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Species Resource Title
Human and Animal Cells A549(RCB0098) Dephosphorylation of branched-chain α-keto acid dehydrogenase E1α (BCKDHA) promotes branched-chain amino acid catabolism and renders cancer cells resistant to X-rays by mitigating DNA damage.
Mice RBRC05198 Consequences of Cre-mediated deletion of Ciz1 exon 5 in mice.
DNA material CSIV-TRE-RfA-UbC-KT (RDB12878) , CS-RfA-ETBsd (RDB07917) Ribosomal S6 kinase (RSK) plays a critical role in DNA damage response via the phosphorylation of histone lysine demethylase KDM4B.
Human and Animal Cells HeLa/Fucci(RCB2812) Vaccinia Virus Arrests and Shifts the Cell Cycle.
Mice RBRC02975 Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation.
Yeast FY21311 Replication stress response in fission yeast differentially depends on maintaining proper levels of Srs2 helicase and Rrp1, Rrp2 DNA translocases.
DNA material CS-RfA-ETBsd (RDB07917) PP1 regulatory subunit NIPP1 regulates transcription of E2F1 target genes following DNA damage.
Human and Animal Cells THP-1(RCB1189) HIV-1 Vpr induces DNA double-strand breaks.
DNA material CSIV-TRE-RfA-UbC-KT (RDB12878) , pENTR-hSLFN5 (RDB20418) , pENTR-hSLFN13 (RDB20419) , pENTR-mSlfn8 (RDB20420) , pENTR-mSlfn9 (RDB20421) , pcDNA3-GFP-mSlfn8 (RDB20422) , pcDNA3-GFP-mSlfn9 (RDB20423) , pcDNA3-GFP-hSLFN5 (RDB20424) , pcDNA3-GFP-hSLFN13 (RDB20425) , pcDNA3-GFP-hSLFN11 (RDB20426) Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.
C.elegans tm4374 , tm6691 , tm2862 Effects of Manganese on Genomic Integrity in the Multicellular Model Organism Caenorhabditis elegans.
C.elegans tm760 , tm776 , tm1146 Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans.
Human and Animal Cells Jurkat(RCB0806) The endocytosis inhibitor dynasore induces a DNA damage response pathway that can be manipulated for enhanced apoptosis.
Human and Animal Cells WI-38 Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations.
Human and Animal Cells MOLT-4(RCB0206) Lineal energy-based evaluation of oxidative DNA damage induced by proton beams and X-rays.
Drosophila DGRC#111109 VCP maintains nuclear size by regulating the DNA damage-associated MDC1-p53-autophagy axis in Drosophila.
Human and Animal Cells B16 , Colon-26(RCB2657) DNA damage enhanced by the attenuation of SLD5 delays cell cycle restoration in normal cells but not in cancer cells.
Human and Animal Cells SRA 01/04(RCB1591) Cell type-dependent induction of DNA damage by 1800 MHz radiofrequency electromagnetic fields does not result in significant cellular dysfunctions.
DNA material pENTR4-H1 (RDB04395) Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses.
Human and Animal Cells CHO-K1(RCB0285) Evaluation of the cell survival curve under radiation exposure based on the kinetics of lesions in relation to dose-delivery time.