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  • 検索条件 : 絞込み (MeSH = Down-Regulation / drug effects*)
生物種 リソース名 タイトル
ヒト・動物細胞 P3/NSI/1-AG4-1(RCB0095) Phorbol ester-induced reversible inactivation of cytotoxic T cell function: correlation with down-regulation of protein kinase C activity.
ヒト・動物細胞 B16F10(RCB2630) Indomethacin inhibits melanogenesis via down-regulation of Mitf mRNA transcription.
ヒト・動物細胞 UE7T-13(RCB2161) Cellular Model of Alzheimer's Disease: Aβ1-42 Peptide Induces Amyloid Deposition and a Decrease in Topo Isomerase IIβ and Nurr1 Expression.
ヒト・動物細胞 A549 Down-Regulation of Claudin-2 Expression by Cyanidin-3-Glucoside Enhances Sensitivity to Anticancer Drugs in the Spheroid of Human Lung Adenocarcinoma A549 Cells.
ヒト・動物細胞 THP-1(RCB1189) , RAW 264(RCB0535) Amelogenin Downregulates Interferon Gamma-Induced Major Histocompatibility Complex Class II Expression Through Suppression of Euchromatin Formation in the Class II Transactivator Promoter IV Region in Macrophages.
ヒト・動物細胞 MIA Paca2(RCB2094) Nab-paclitaxel interrupts cancer-stromal interaction through C-X-C motif chemokine 10-mediated interleukin-6 downregulation in vitro.
ヒト・動物細胞 B16/BL6(RCB2638) In Vivo Antitumor Effects of MK615 Led by PD-L1 Downregulation.
ヒト・動物細胞 MH7A(RCB1512) Glucosamine Downregulates the IL-1β-Induced Expression of Proinflammatory Cytokine Genes in Human Synovial MH7A Cells by O-GlcNAc Modification-Dependent and -Independent Mechanisms.
ヒト・動物細胞 RAW 264(RCB0535) Down-regulation of inflammatory mediator synthesis and infiltration of inflammatory cells by MMP-3 in experimentally induced rat pulpitis.
ヒト・動物細胞 MKN45(RCB1001 , MKN28(RCB1000) Downregulation of histone deacetylase 1 by microRNA-520h contributes to the chemotherapeutic effect of doxorubicin.
ヒト・動物細胞 DT40(RCB1464) , ΔBLM-DT40(RCB1811) , ΔWRN-DT40(RCB1812) 3EZ,20Ac-ingenol, a catalytic inhibitor of topoisomerases, downregulates p-Akt and induces DSBs and apoptosis of DT40 cells.
ヒト・動物細胞 γ-Oryzanol reduces adhesion molecule expression in vascular endothelial cells via suppression of nuclear factor-κB activation.
ヒト・動物細胞 MC3T3-E1(RCB1126) 1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130.
ヒト・動物細胞 MC3T3-E1(RCB1126) Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.
ヒト・動物細胞 J774.1 Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages.
遺伝子材料 CSII-CMV-MCS-IRES2-Venus (RDB04383) The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.
ヒト・動物細胞 RAW 264(RCB0535) Dilazep decreases lipopolysaccharide-induced nitric oxide and TNF-alpha synthesis in RAW 264 cells.
ヒト・動物細胞 U-937 DE-4(RCB0435) Halichlorine reduces monocyte adhesion to endothelium through the suppression of nuclear factor-kappaB activation.
ヒト・動物細胞 RAW 264(RCB0535) Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1β and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).
ヒト・動物細胞 MCF7(RCB1904) , LNCap.FGC(RCB2144) Xenoestrogens down-regulate aryl-hydrocarbon receptor nuclear translocator 2 mRNA expression in human breast cancer cells via an estrogen receptor alpha-dependent mechanism.