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  • Search Condition : Filter (MeSH = Down-Regulation / genetics*)
Species Resource
Silkworms ? Establishment of a novel in vivo sex-specific splicing assay system to identify a trans-acting factor that negatively regulates splicing of Bombyx mori dsx female exons.
Drosophila DGRC#111469 Genetic elevation of sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila.
Human and Animal Cells ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer.
Human and Animal Cells MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell line.
Human and Animal Cells Soy protein isolate down-regulates caveolin-1 expression to suppress osteoblastic cell senescence pathways.
Human and Animal Cells Fibulin 1 is downregulated through promoter hypermethylation in gastric cancer.
Human and Animal Cells Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis.
Human and Animal Cells Aryl hydrocarbon receptor nuclear translocator in human liver is regulated by miR-24.
Human and Animal Cells RAW 264 Down-regulation of beta2-adrenergic receptor expression by exercise training increases IL-12 production by macrophages following LPS stimulation.
Human and Animal Cells HFL-I Glycyrrhizin and related compounds down-regulate production of inflammatory chemokines IL-8 and eotaxin 1 in a human lung fibroblast cell line.
Human and Animal Cells C2C12 (RCB0987) Notch2 negatively regulates myofibroblastic differentiation of myoblasts.
Human and Animal Cells A cell line with characteristics of the periodontal ligament fibroblasts is negatively regulated for mineralization and Runx2/Cbfa1/Osf2 activity, part of which can be overcome by bone morphogenetic protein-2.