When you enter multiple keywords separated by space, your search will contain results that match any of the keywords (OR search).
  • 18 Hits
  • Search Condition : Filter (MeSH = Drug Design*)
Species Resource Title
Human and Animal Cells MKN74(RCB1002) , DU145(RCB2143) , PC-3(RCB2145) Synthesis and biological evaluation of new rhodanine analogues bearing 2-chloroquinoline and benzo[h]quinoline scaffolds as anticancer agents.
Human and Animal Cells PC-9(RCB4455) Design, synthesis and evaluation of the osimertinib analogue (C-005) as potent EGFR inhibitor against NSCLC.
Human and Animal Cells PC-9(RCB4455) Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
Human and Animal Cells A549(RCB0098) Logical design of an anti-cancer agent targeting the plant homeodomain in Pygopus2.
Human and Animal Cells MCF7(RCB1904) , A549(RCB0098) Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors.
Human and Animal Cells HeLa(RCB0007) Design and synthesis of temperature-responsive polymer/silica hybrid nanoparticles and application to thermally controlled cellular uptake.
Human and Animal Cells NCC-RbC-51(RCB2206) Designing and enhancing the antifungal activity of corneal specific cell penetrating peptide using gelatin hydrogel delivery system.
Human and Animal Cells A549(RCB0098) , MCF7(RCB1904) Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity.
Human and Animal Cells HeLa(RCB0007) Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.
Human and Animal Cells Ba/F3(RCB0805) , A431 Generation of an anti-desmoglein 3 antibody without pathogenic activity of pemphigus vulgaris for therapeutic application to squamous cell carcinoma.
General Microbes JCM 20379 Identification of a novel class of small compounds with anti-tuberculosis activity by in silico structure-based drug screening.
Mice RBRC00806 ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice.
Pathogenic microorganisms ? Target validation and ligand development for a pathogenic fungal profilin, using a knock-down strain of pathogenic yeast Candida glabrata and structure-based ligand design.
Human and Animal Cells Colon-26(RCB2657) Design and evaluation of thioalkylated mannose-modified dendrimer (G3)/α-cyclodextrin conjugates as antigen-presenting cell-selective siRNA carriers.
Human and Animal Cells Indazoles as potential c-Met inhibitors: design, synthesis and molecular docking studies.
Human and Animal Cells MCF7(RCB1904) Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design.
Silkworms Characterization of arylalkylamine N-acetyltransferase from silkmoth (Antheraea pernyi) and pesticidal drug design based on the baculovirus-expressed enzyme.
DNA material pCMV-SP1 (RDB04267) , pGEX-SP1 (RDB05699) , pGEX-hMAZ (RDB05701) , pCMV-MAZ (RDB03219). G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.