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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Drug Evaluation, Preclinical / methods*)
生物種 リソース名 タイトル
ゼブラフィッシュ Tg(Huc:Kaede)rw0130a Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae.
ゼブラフィッシュ Tg(Tcf/Lef-miniP:dGFP) Protocol for rapid assessment of the efficacy of novel Wnt inhibitors using zebrafish models.
ヒト・動物細胞 A549(RCB0098) Image-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerization.
ヒト・動物細胞 LLC-GA5-CoL150(RCB0871) Development of Simplified in Vitro P-Glycoprotein Substrate Assay and in Silico Prediction Models To Evaluate Transport Potential of P-Glycoprotein.
遺伝子材料 CSII-CMV-MCS-IRES2-Venus (RDB04383) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction.
カイコ [A Silkworm Infection Model to Evaluate Antifungal Drugs for Cryptococcosis].
ヒト・動物細胞 293T(RCB2202) , HeLa(RCB0007) A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome.
ヒト・動物細胞 253G1(HPS0002) Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells.
ヒト・動物細胞 LLC-GA5-CoL150(RCB0871) The Impact of Endogenous Breast Cancer Resistance Protein on Human P-Glycoprotein-Mediated Transport Assays Using LLC-PK1 Cells Transfected With Human P-Glycoprotein.
ヒト・動物細胞 MDCK(RCB0995) An Application of Photoactivatable Substrate for the Evaluation of Epithelial-mesenchymal Transition Inhibitors.
ヒト・動物細胞 SK-N-SH(RCB0426) Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
一般微生物 JCM 20379 In silico structure-based drug screening of novel antimycobacterial pharmacophores by DOCK-GOLD tandem screening.
ヒト・動物細胞 C2C12(RCB0987) Facile and rapid generation of 3D chemical gradients within hydrogels for high-throughput drug screening applications.
ヒト・動物細胞 MC3T3-E1(RCB1126) Development of high-throughput screening system for osteogenic drugs using a cell-based sensor.
ヒト・動物細胞 J774.1(RCB0431) Screening of Chinese herbal drug extracts for inhibitory activity on nitric oxide production and identification of an active compound of Zanthoxylum bungeanum.
ヒト・動物細胞 Development of a highly sensitive cytotoxicity assay system for CYP3A4-mediated metabolic activation.
ヒト・動物細胞 MCF7(RCB1904) Use of cell-based screening to identify small-molecule compounds that modulate claudin-4 expression.
一般微生物 JCM 4073 , JCM 4297 , JCM 4523 , JCM 4526 , JCM 4667 , JCM 4775 Prescreening bacterial colonies for bioactive molecules with Janus plates, a SBS standard double-faced microbial culturing system.
遺伝子材料 , ヒト・動物細胞 pRSET-hp38 (RDB08172) , pRSET-hp38K53A (RDB08173) , pRSET-hp38T106M (RDB08174) , pRSET-GST-hp38 (RDB08178) , HeLa(RCB0007) A p38 mitogen-activated protein kinase inhibitor screening method using growth recovery of Escherichia coli as an index.
カイコ Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assay.