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  • Search Condition : Filter (MeSH = Drug Resistance, Neoplasm / genetics*)
Species Resource Title
Human and Animal Cells U-87 MG(RCB0419) Adenovirus-mediated p16 gene transfer prevents drug-induced cell death through G1 arrest in human glioma cells.
Human and Animal Cells HuH-7(RCB1366) The BAFF/NFκB axis is crucial to interactions between sorafenib-resistant HCC cells and cancer-associated fibroblasts.
Human and Animal Cells Ba/F3(RCB0805) Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.
Human and Animal Cells 293T(RCB2202) SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2.
Human and Animal Cells Ba/F3(RCB0805) Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS-MAPK Reactivation.
Human and Animal Cells A549(RCB0098) Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells.
Human and Animal Cells Ba/F3 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
Human and Animal Cells MG-63(RCB1890) Ca2+ -activated K+ channel KCa 1.1 as a therapeutic target to overcome chemoresistance in three-dimensional sarcoma spheroid models.
Human and Animal Cells DT40(RCB1464) Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation.
Human and Animal Cells Ba/F3(RCB0805) Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.
Human and Animal Cells A549(RCB0098) , LC-2/ad(RCB0440) Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.
Human and Animal Cells RPMI8226(RCB3010) The MIP-1α autocrine loop contributes to decreased sensitivity to anticancer drugs.
Human and Animal Cells HuCCT1(RCB1960) , RBE(RCB1292) , SSP-25(RCB1293) , HuH-28(RCB1943) TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma.
Human and Animal Cells Ba/F3 Mechanisms of Resistance to NTRK Inhibitors and Therapeutic Strategies in NTRK1-Rearranged Cancers.
Human and Animal Cells MIA Paca2(RCB2094) Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors.
Human and Animal Cells TFK-1(RCB2537) , HuCCT1(RCB1960) Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins.
Human and Animal Cells Ba/F3 Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer.
Human and Animal Cells MRC-5(RCB0218) MET Copy Number Gain Is Associated with Gefitinib Resistance in Leptomeningeal Carcinomatosis of EGFR-mutant Lung Cancer.
Human and Animal Cells HL60 , KG-1a(RCB1928) , NALM-6(RCB1933) , MOLT-4(RCB0206) , SKW-3(RCB1168) High expression of PSF1 promotes drug resistance and cell cycle transit in leukemia cells.
Human and Animal Cells HKBML(RCB0820) GSEA-assisted gene signatures valid for combinations of prognostic markers in PCNSL.