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  • Search Condition : Filter (MeSH = Endodeoxyribonucleases / metabolism*)
Species Resource Title
Human and Animal Cells HeLa/Fucci(RCB2812) The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells.
C.elegans tm3222 Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Human and Animal Cells 293T(RCB2202) Genome editing in mammalian cells using the CRISPR type I-D nuclease.
Human and Animal Cells 409B2(HPS0076) Rapid repair of human disease-specific single-nucleotide variants by One-SHOT genome editing.
C.elegans tm6691 , tm4374 , tm2862 , tm2572 UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
C.elegans tm3468 LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis.
DNA material Genomic DNA of Thermococcus kodakarensis JCM 12380 T (JGD07705). Bacterial EndoMS/NucS acts as a clamp-mediated mismatch endonuclease to prevent asymmetric accumulation of replication errors.
Prokaryotes E. coli Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria.
C.elegans tm1159 Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G.
C.elegans tm3222 , tm2595 Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization.
Medaka d-rR/TOKYO (MT837) , OK-Cab (MT830) , DJ-1(delta7) (MT972) , MC4R(delta7) (MT973) , MC4R(delta11) (MT974) , Sakyo (WS1164) Design, evaluation, and screening methods for efficient targeted mutagenesis with transcription activator-like effector nucleases in medaka.
C.elegans tm890 Autonomous and non-autonomous roles of DNase II during cell death in C. elegans embryos.
Human and Animal Cells Jurkat A synthesized nostocionone derivative potentiates programmed cell death in human T-cell leukemia Jurkat cells through mitochondria via the release of endonuclease G.
Drosophila DGRC#140133 Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.
Prokaryotes E. coli JW1852? , JW3672? UspB, a member of the sigma-S regulon, facilitates RuvC resolvase function.
Rats , Human and Animal Cells F344/Stm(strainID=266) , Rat-1(RCB1830) Simple knockout by electroporation of engineered endonucleases into intact rat embryos.
Drosophila The balancer chromosomes were CyO and TM3 (Kyoto Stock Center). The double-stranded break-forming activity of plant SPO11s and a novel rice SPO11 revealed by a Drosophila bioassay.
Mice RBRC01725 , RBRC04020 DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
Rats SHR/Kyo(strainID=9) Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.
C.elegans T04A8.15 = him-18 , tm2181 , tm1937 Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates.